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This enhancing effect on glucagon secretion makes lone GIP agonists unsuitable for the treatment of T2DM [23]

314 Preliminary data from preclinical models 315 and a phase I clinical trial 316,317 have indicated that RP-A501 treatment increases cardiac LAMP2B expression, leading to significant histological improvements in cardiac tissue

J Endocrinol , 262: e240058, 2024

The gamma-nitrogen of glutamine is used in five reactions in de novo nucleotide synthesis, and its bioavailability controls de novo biosynthesis of pyrimidines and purines (Fig

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